Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCT All Species: 9.09
Human Site: Y1905 Identified Species: 22.22
UniProt: P09848 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09848 NP_002290.2 1927 218573 Y1905 L A F L S Y K Y C K R S K Q G
Chimpanzee Pan troglodytes XP_522655 1012 116155 F991 A F I A F L F F A F I I S L S
Rhesus Macaque Macaca mulatta XP_001096426 1928 218172 Y1906 L A F L S Y K Y C K R S K Q G
Dog Lupus familis XP_541018 1371 156201 C1350 A F L S Y K Y C K H S K Q G K
Cat Felis silvestris
Mouse Mus musculus O35082 1014 116407 F993 V F I S F L V F T F I I S L A
Rat Rattus norvegicus Q02401 1928 217249 T1906 L A F L T Y N T G R R S K Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515349 1797 200802 V1776 V C N I W V L V T I L P L M M
Chicken Gallus gallus NP_001104816 1935 219845 S1914 A L G L A L I S Y K Y G T I S
Frog Xenopus laevis NP_001106299 607 69234 L586 A F L I A A V L G I V L L S V
Zebra Danio Brachydanio rerio XP_001336765 1897 215948 L1874 V I F L V F G L V R T S K K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.1 95.9 62.9 N.A. 23 78 N.A. 55.4 63.6 22.2 53.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 34.9 97.8 66.9 N.A. 35 87.1 N.A. 65.9 77.9 27 69.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 0 66.6 N.A. 0 13.3 0 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 6.6 N.A. 13.3 80 N.A. 13.3 20 13.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 30 0 10 20 10 0 0 10 0 0 0 0 0 10 % A
% Cys: 0 10 0 0 0 0 0 10 20 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 40 40 0 20 10 10 20 0 20 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 20 0 0 10 0 10 30 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 20 20 0 0 10 0 0 20 20 20 0 10 0 % I
% Lys: 0 0 0 0 0 10 20 0 10 30 0 10 40 10 10 % K
% Leu: 30 10 20 50 0 30 10 20 0 0 10 10 20 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 30 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 20 30 0 0 0 0 % R
% Ser: 0 0 0 20 20 0 0 10 0 0 10 40 20 10 20 % S
% Thr: 0 0 0 0 10 0 0 10 20 0 10 0 10 0 0 % T
% Val: 30 0 0 0 10 10 20 10 10 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 30 10 20 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _